Analysis of the dihydrofolate reductase-thymidylate synthase gene sequences in <it>Plasmodium vivax </it>field isolates that failed chloroquine treatment
<p>Abstract</p> <p>Background</p> <p>To use pyrimethamine as an alternative anti-malarial drug for chloroquine-resistant malaria parasites, it was necessary to determine the enzyme's genetic variation in dihydrofolate reductase-thymidylate syntase (DHFR-TS) among K...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-11-01
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Series: | Malaria Journal |
Online Access: | http://www.malariajournal.com/content/9/1/331 |