Micropatterned co-culture of hepatocyte spheroids layered on non-parenchymal cells to understand heterotypic cellular interactions

Microfabrication and micropatterning techniques in tissue engineering offer great potential for creating and controlling cellular microenvironments including cell–matrix interactions, soluble stimuli and cell–cell interactions. Here, we present a novel approach to generate layered patterning of hepa...

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Bibliographic Details
Main Author: Hidenori Otsuka, Kohei Sasaki, Saya Okimura, Masako Nagamura and Yuichi Nakasone
Format: Article
Language:English
Published: Taylor & Francis Group 2013-01-01
Series:Science and Technology of Advanced Materials
Online Access:http://dx.doi.org/10.1088/1468-6996/14/6/065003