PhenoMapping: A protocol to map cellular phenotypes to metabolic bottlenecks, identify conditional essentiality, and curate metabolic models

Summary: Targeted identification of cellular processes responsible for a phenotype is of major importance in guiding efforts in bioengineering and medicine. Genome-scale metabolic models (GEMs) are widely used to integrate various types of omics data and study the cellular physiology under different...

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Bibliographic Details
Main Authors: Anush Chiappino-Pepe, Vassily Hatzimanikatis
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166720302677

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