Combined Effects of Baicalein and Docetaxel on Apoptosis in 8505c Anaplastic Thyroid Cancer Cells via Downregulation of the ERK and Akt/mTOR Pathways

Combined Effects of Baicalein and Docetaxel on Apoptosis in 8505c Anaplastic Thyroid Cancer Cells via Downregulation of the ERK and Akt/mTOR Pathways

BackgroundAnaplastic thyroid cancer (ATC) is one of the most lethal human malignancies. Docetaxel, a microtubule stabilizer, is a common chemotherapeutic agent used to treat various metastatic cancers. However, prolonged use results in various side effects and drug resistance. Flavonoids, such as ba...

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Bibliographic Details
Main Authors: Chan Ho Park, Se Eun Han, Il Seong Nam-Goong, Young Il Kim, Eun Sook Kim
Format: Article
Language:English
Published: Academya Publishing Co. 2018-03-01
Series:Endocrinology and Metabolism
Subjects:
Baicalein
Thyroid carcinoma, anaplastic
Angiogenesis
Apoptosis
Combination therapy
Docetaxel
8505c cells
Online Access:https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-121.pdf

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