Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.

Bibliographic Details
Main Authors: Peter G. Farlie, Nadia M. Davidson, Naomi L. Baker, Mai Raabus, Kelly N. Roeszler, Claire Hirst, Andrew Major, Mylene M. Mariette, David M. Lambert, Alicia Oshlack, Craig A. Smith
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00112-7

Internet

https://doi.org/10.1038/s41467-017-00112-7

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