B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition

B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition

EBV is a human pathogen associated with several malignancies. A key aspect of lifelong virus persistence is the ability to switch between latent and lytic replication modes.

Bibliographic Details
Main Authors: Yan Chen, Devin N. Fachko, Nikita S. Ivanov, Rebecca L. Skalsky
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00093-21
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spelling doaj-d3965c4c42f94dd780bd32190645d6f52021-09-21T20:34:55ZengAmerican Society for MicrobiologymSphere2379-50422021-04-016210.1128/mSphere.00093-21B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 InhibitionYan Chen0Devin N. Fachko1Nikita S. Ivanov2Rebecca L. Skalsky3https://orcid.org/0000-0003-2967-9478Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA EBV is a human pathogen associated with several malignancies. A key aspect of lifelong virus persistence is the ability to switch between latent and lytic replication modes.https://journals.asm.org/doi/10.1128/mSphere.00093-21
collection DOAJ
language English
format Article
sources DOAJ
author Yan Chen
Devin N. Fachko
Nikita S. Ivanov
Rebecca L. Skalsky
spellingShingle Yan Chen
Devin N. Fachko
Nikita S. Ivanov
Rebecca L. Skalsky
B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition
mSphere
author_facet Yan Chen
Devin N. Fachko
Nikita S. Ivanov
Rebecca L. Skalsky
author_sort Yan Chen
title B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition
title_short B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition
title_full B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition
title_fullStr B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition
title_full_unstemmed B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition
title_sort b cell receptor-responsive mir-141 enhances epstein-barr virus lytic cycle via foxo3 inhibition
publisher American Society for Microbiology
series mSphere
issn 2379-5042
publishDate 2021-04-01
description EBV is a human pathogen associated with several malignancies. A key aspect of lifelong virus persistence is the ability to switch between latent and lytic replication modes.
url https://journals.asm.org/doi/10.1128/mSphere.00093-21
work_keys_str_mv AT yanchen bcellreceptorresponsivemir141enhancesepsteinbarrviruslyticcycleviafoxo3inhibition
AT devinnfachko bcellreceptorresponsivemir141enhancesepsteinbarrviruslyticcycleviafoxo3inhibition
AT nikitasivanov bcellreceptorresponsivemir141enhancesepsteinbarrviruslyticcycleviafoxo3inhibition
AT rebeccalskalsky bcellreceptorresponsivemir141enhancesepsteinbarrviruslyticcycleviafoxo3inhibition
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