Cytokine Detection and Modulation in Acute Graft vs. Host Disease in Mice
A murine model for acute lethal graft vs. host disease (GVHD) was used to study the role that a number of cytokines play in the development of lethal GVHD. In this study we focused on the role of IL-1, IL-2, IL-4, IL-6, IFN-γ and TNF-α. Lethally irradiated (C57BL × CBA)F1 mice were reconstituted eit...
Main Authors: | A. C. Knulst, G. J. M. Tibbe, C. Bril-Bazuin, E. G. Breedland, A. van Oudenaren, R. Benner, H. F. J. Savelkoul |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
1994-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935194000062 |
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