Use and cardiovascular safety of transdermal and other granisetron preparations in cancer management

Jay W Mason,1 Thomas E Moon2 1School of Medicine, University of Utah, Salt Lake City, UT, 2Tarizona eHealth Services, Inc, Emeryville, CA, USA Abstract: 5-HT3 antagonists have been available as oral and intravenous preparations for decades. The availability more recently of transdermal granisetron a...

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Bibliographic Details
Main Authors: Mason JW, Moon TE
Format: Article
Language:English
Published: Dove Medical Press 2013-07-01
Series:Cancer Management and Research
Online Access:http://www.dovepress.com/use-and-cardiovascular-safety-of-transdermal-and-other-granisetron-pre-a13822
Description
Summary:Jay W Mason,1 Thomas E Moon2 1School of Medicine, University of Utah, Salt Lake City, UT, 2Tarizona eHealth Services, Inc, Emeryville, CA, USA Abstract: 5-HT3 antagonists have been available as oral and intravenous preparations for decades. The availability more recently of transdermal granisetron and the anticipated availability of a subcutaneous granisetron preparation have provided helpful alternatives to patients, and these preparations have been shown to have less potential to prolong QT than other drugs in the class. Keywords: chemotherapy-induced nausea, vomiting, granisetron, QT prolongation
ISSN:1179-1322