New Constituents from the Korean Sponge Plakortis simplex

Six new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antif...

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Main Authors:	Ok-Hwa Kang, Buyng Su Hwang, Jung-Rae Rho, Dong-Yeul Kwon, Jung Soon Oh
Format:	Article
Language:	English
Published:	MDPI AG 2013-11-01
Series:	Marine Drugs
Subjects:	Plakortis simplex cyclic peroxide cyclic peroxyketal pyridinium NMR
Online Access:	http://www.mdpi.com/1660-3397/11/11/4407

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spelling	doaj-d37eeb968abe490d91ec5148aff888bd2020-11-24T20:54:52ZengMDPI AGMarine Drugs1660-33972013-11-0111114407441810.3390/md11114407New Constituents from the Korean Sponge Plakortis simplexOk-Hwa KangBuyng Su HwangJung-Rae RhoDong-Yeul KwonJung Soon OhSix new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.http://www.mdpi.com/1660-3397/11/11/4407Plakortis simplexcyclic peroxidecyclic peroxyketalpyridiniumNMR
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ok-Hwa Kang Buyng Su Hwang Jung-Rae Rho Dong-Yeul Kwon Jung Soon Oh
spellingShingle	Ok-Hwa Kang Buyng Su Hwang Jung-Rae Rho Dong-Yeul Kwon Jung Soon Oh New Constituents from the Korean Sponge Plakortis simplex Marine Drugs Plakortis simplex cyclic peroxide cyclic peroxyketal pyridinium NMR
author_facet	Ok-Hwa Kang Buyng Su Hwang Jung-Rae Rho Dong-Yeul Kwon Jung Soon Oh
author_sort	Ok-Hwa Kang
title	New Constituents from the Korean Sponge Plakortis simplex
title_short	New Constituents from the Korean Sponge Plakortis simplex
title_full	New Constituents from the Korean Sponge Plakortis simplex
title_fullStr	New Constituents from the Korean Sponge Plakortis simplex
title_full_unstemmed	New Constituents from the Korean Sponge Plakortis simplex
title_sort	new constituents from the korean sponge plakortis simplex
publisher	MDPI AG
series	Marine Drugs
issn	1660-3397
publishDate	2013-11-01
description	Six new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.
topic	Plakortis simplex cyclic peroxide cyclic peroxyketal pyridinium NMR
url	http://www.mdpi.com/1660-3397/11/11/4407
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New Constituents from the Korean Sponge Plakortis simplex

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