Head and Neck Cancer Stem Cell-Enriched Spheroid Model for Anticancer Compound Screening

Head and Neck Cancer Stem Cell-Enriched Spheroid Model for Anticancer Compound Screening

Cancer stem cells (CSCs), a rare cell population in tumors, are resistant to conventional chemotherapy and thus responsible for tumor recurrence. To screen for active compounds targeting CSCs, a good CSC-enriched model compatible with high-throughput screening (HTS) is needed. Here, we describe a ne...

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Bibliographic Details
Main Authors: Larisa Goričan, Boris Gole, Uroš Potočnik
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
head and neck squamous cell carcinoma
cancer stem cells
3-D/spheroid culture/model
high-throughput screening
anticancer stem cell compounds
ATRA
Online Access:https://www.mdpi.com/2073-4409/9/7/1707

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