Exposure to TiO<sub>2</sub> Nanostructured Aerosol Induces Specific Gene Expression Profile Modifications in the Lungs of Young and Elderly Rats

Exposure to TiO<sub>2</sub> Nanostructured Aerosol Induces Specific Gene Expression Profile Modifications in the Lungs of Young and Elderly Rats

Although aging is associated with a higher risk of developing respiratory pathologies, very few studies have assessed the impact of age on the adverse effects of inhaled nanoparticles. Using conventional and transcriptomic approaches, this study aimed to compare in young (12–13-week-old) and elderly...

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Bibliographic Details
Main Authors: Sarah A. Valentino, Laëtitia Chézeau, Carole Seidel, Sylvie Sébillaud, Mylène Lorcin, Monique Chalansonnet, Frédéric Cosnier, Laurent Gaté
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nanomaterials
Subjects:
inhalation
titanium dioxide
lung
age
transcriptomics
rat
Online Access:https://www.mdpi.com/2079-4991/11/6/1466

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