Association of MDM2 expression with shorter progression-free survival and overall survival in patients with advanced pancreatic cancer treated with gemcitabine-based chemotherapy.

This study evaluated the prognostic roles of murine double minute 2 (MDM2) and p53 in pancreatic cancer patients treated with gemcitabine-based chemotherapy. A total of 137 advanced or recurrent adenocarcinoma patients who were treated with gemcitabine-based palliative chemotherapy were reviewed, se...

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Bibliographic Details
Main Authors: Shih-Hung Yang, Jen-Chieh Lee, Jhe-Cyuan Guo, Sung-Hsin Kuo, Yu-Wen Tien, Ting-Chun Kuo, Ann-Lii Cheng, Kun-Huei Yeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5498069?pdf=render