A protocol for transdifferentiation of human cardiac fibroblasts into endothelial cells via activation of innate immunity

Summary: Endothelial cells (ECs) have emerged as key pathogenic players in cardiac disease due to their proximity with cardiomyocytes. Induced pluripotent stem cells (iPSCs) have been employed to generate ECs. However, it may be more clinically relevant to transdifferentiate fibroblasts into ECs dir...

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Bibliographic Details
Main Authors: Chun Liu, Pedro Medina, Dilip Thomas, Ian Y. Chen, Karim Sallam, Danish Sayed, Nazish Sayed
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672100263X

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