A protocol for transdifferentiation of human cardiac fibroblasts into endothelial cells via activation of innate immunity
Summary: Endothelial cells (ECs) have emerged as key pathogenic players in cardiac disease due to their proximity with cardiomyocytes. Induced pluripotent stem cells (iPSCs) have been employed to generate ECs. However, it may be more clinically relevant to transdifferentiate fibroblasts into ECs dir...
Main Authors: | Chun Liu, Pedro Medina, Dilip Thomas, Ian Y. Chen, Karim Sallam, Danish Sayed, Nazish Sayed |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-06-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S266616672100263X |
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