PROTECTIVE EFFECT OF POLYMYXINE B AND NIFEDIPINE ON DIABETIC COMPLICATIONS IN RAT: ROLE OF PROTEIN KINASE C

Patients with diabetes mellitus (DM), experience significant morbidity and mortality from microvascular retinopathy, nephropathy and neuropathy. Hyperglycemia can induce diabetic complications through multiple pathways. Activation of protein kinase C (PKC) by hyperglycemia is one of the pathways whi...

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Bibliographic Details
Main Authors: H. Mehrani, R. Rezae
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2003-12-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/2667