CCNB1 affects cavernous sinus invasion in pituitary adenomas through the epithelial–mesenchymal transition

CCNB1 affects cavernous sinus invasion in pituitary adenomas through the epithelial–mesenchymal transition

Abstract Background To investigate the relationship between cyclin B1 (CCNB1) gene expression and cavernous sinus invasion in pituitary adenomas. Methods Twenty-four pituitary adenoma tissue samples were examined by RT-qPCR and Western blot to assess the mRNA expression levels and protein levels of...

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Bibliographic Details
Main Authors: Bin Li, Jianhua Cheng, Hongyun Wang, Sida Zhao, Haibo Zhu, Chuzhong Li, Yazhuo Zhang, Peng Zhao
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Translational Medicine
Subjects:
Pituitary adenoma
Cavernous sinus invasion
CCNB1 gene
Epithelial–mesenchymal transition
E-Cadherin
N-Cadherin
Online Access:http://link.springer.com/article/10.1186/s12967-019-2088-8

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