Noncanonical farnesoid X receptor signaling inhibits apoptosis and impedes liver fibrosisResearch in context

Noncanonical farnesoid X receptor signaling inhibits apoptosis and impedes liver fibrosisResearch in context

Background: Hepatocyte is particularly vulnerable to apoptosis, a hallmark of many liver diseases. Although pro-apoptotic mechanisms have been extensively explored, less is known about the hepatocyte-specific anti-apoptotic molecular events and it lacks effective approach to combat hepatocyte apopto...

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Main Authors: Hong Wang, Chaoliang Ge, Jiyu Zhou, Yitong Guo, Shuang Cui, Ningning Huang, Tingting Yan, Lijuan Cao, Yuan Che, Qiuling Zheng, Xiao Zheng, Frank J. Gonzalez, Guangji Wang, Haiping Hao
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418304468

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