Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones

A highly efficient protocol for the one-pot multi-component condensation of acetophenones with aromatic aldehydes, acetonitrile and acetyl chloride in the presence of melamine trisulfonic acid (MTSA) as a highly efficient and recyclable sulfonic acid-containing catalyst at room temperature is descri...

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Main Author: Abdolkarim Zare
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2012/173197
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spelling doaj-d33a21ee9f01493596a3ef0d81255d2c2020-11-24T20:54:32ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102012-01-01942322233110.1155/2012/173197Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido KetonesAbdolkarim Zare0Department of Chemistry, Payame Noor University, PO BOX 19395-4697, Tehran, IranA highly efficient protocol for the one-pot multi-component condensation of acetophenones with aromatic aldehydes, acetonitrile and acetyl chloride in the presence of melamine trisulfonic acid (MTSA) as a highly efficient and recyclable sulfonic acid-containing catalyst at room temperature is described. In this method, β-acetamido ketone derivatives are obtained in high to excellent yields and in relatively short reaction times.http://dx.doi.org/10.1155/2012/173197
collection DOAJ
language English
format Article
sources DOAJ
author Abdolkarim Zare
spellingShingle Abdolkarim Zare
Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones
E-Journal of Chemistry
author_facet Abdolkarim Zare
author_sort Abdolkarim Zare
title Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones
title_short Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones
title_full Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones
title_fullStr Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones
title_full_unstemmed Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones
title_sort melamine trisulfonic acid as a highly efficient and reusable catalyst for the synthesis of β-acetamido ketones
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2012-01-01
description A highly efficient protocol for the one-pot multi-component condensation of acetophenones with aromatic aldehydes, acetonitrile and acetyl chloride in the presence of melamine trisulfonic acid (MTSA) as a highly efficient and recyclable sulfonic acid-containing catalyst at room temperature is described. In this method, β-acetamido ketone derivatives are obtained in high to excellent yields and in relatively short reaction times.
url http://dx.doi.org/10.1155/2012/173197
work_keys_str_mv AT abdolkarimzare melaminetrisulfonicacidasahighlyefficientandreusablecatalystforthesynthesisofbacetamidoketones
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