The impact of the co-registration technique and analysis methodology in comparison studies between advanced imaging modalities and whole-mount-histology reference in primary prostate cancer

The impact of the co-registration technique and analysis methodology in comparison studies between advanced imaging modalities and whole-mount-histology reference in primary prostate cancer

Abstract Comparison studies using histopathology as standard of reference enable a validation of the diagnostic performance of imaging methods. This study analysed (1) the impact of different image-histopathology co-registration pathways, (2) the impact of the applied data analysis method and (3) in...

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Bibliographic Details
Main Authors: Constantinos Zamboglou, Maria Kramer, Selina Kiefer, Peter Bronsert, Lara Ceci, August Sigle, Wolfgang Schultze-Seemann, Cordula A. Jilg, Tanja Sprave, Thomas F. Fassbender, Nils H. Nicolay, Juri Ruf, Matthias Benndorf, Anca L. Grosu, Simon K. B. Spohn
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85028-5

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