Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea

Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea

Translation initiation factor 5A (IF5A) is essential and highly conserved in Eukarya (eIF5A) and Archaea (aIF5A). The activity of IF5A requires hypusine, a posttranslational modification synthesized in Eukarya from the polyamine precursor spermidine. Intracellular polyamine analyses revealed that ag...

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Bibliographic Details
Main Authors:	Laurence Prunetti, Michael Graf, Ian K. Blaby, Lauri Peil, Andrea M. Makkay, Agata L. Starosta, R. Thane Papke, Tairo Oshima, Daniel N. Wilson, Valérie de Crécy-Lagard
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Archaea
Online Access:	http://dx.doi.org/10.1155/2016/7316725

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