False Negative NIPT Results: Risk Figures for Chromosomes 13, 18 and 21 Based on Chorionic Villi Results in 5967 Cases and Literature Review.

False Negative NIPT Results: Risk Figures for Chromosomes 13, 18 and 21 Based on Chorionic Villi Results in 5967 Cases and Literature Review.

Non-invasive prenatal testing (NIPT) demonstrated a small chance for a false negative result. Since the "fetal" DNA in maternal blood originates from the cytotrophoblast of chorionic villi (CV), some false negative results will have a biological origin. Based on our experience with cytogen...

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Bibliographic Details
Main Authors: Diane Van Opstal, Malgorzata I Srebniak, Joke Polak, Femke de Vries, Lutgarde C P Govaerts, Marieke Joosten, Attie T J I Go, Maarten F C M Knapen, Cardi van den Berg, Karin E M Diderich, Robert-Jan H Galjaard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4714811?pdf=render

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