Derivation of the clinical grade human embryonic stem cell line RCe020-a (RC-16)

Derivation of the clinical grade human embryonic stem cell line RCe020-a (RC-16)

The human embryonic stem cell line RCe020-A (RC-16) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived...

Full description

Bibliographic Details
Main Authors: P.A. De Sousa, B.J. Tye, K. Bruce, P. Dand, G. Russell, D.M. Collins, A. Greenshields, K. McDonald, H. Bradburn, A. Laurie, J.M. Downie, M. Bateman, A. Courtney
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116300137
Description
Summary:The human embryonic stem cell line RCe020-A (RC-16) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a failed to fertilise oocyte voluntarily donated as unsuitable or surplus to fertility requirements following informed consent. RCe020-A (RC-16) shows normal pluripotency marker expression and differentiates to mesoderm and potentially ectoderm in vitro. It has an abnormal 47XX, +14, i(20)(q10) female karyotype and microsatellite PCR identity, HLA and blood group typing data is available.
ISSN:1873-5061
1876-7753

Similar Items