The Prognostic Value of Androgen Receptor Splice Variant 7 in Castration-Resistant Prostate Cancer Treated With Novel Hormonal Therapy or Chemotherapy: A Systematic Review and Meta-analysis

The Prognostic Value of Androgen Receptor Splice Variant 7 in Castration-Resistant Prostate Cancer Treated With Novel Hormonal Therapy or Chemotherapy: A Systematic Review and Meta-analysis

PurposeThis study aimed to evaluate the prognostic role of AR-V7 in terms of prostate-specific antigen (PSA) response, progression-free survival (PFS), and overall survival (OS) in CRPC patients treated with novel hormonal therapy (NHT) (Abiraterone and Enzalutamide) or taxane-based chemotherapy (Do...

Full description

Bibliographic Details
Main Authors:	Zhize Wang, Haixiang Shen, Nieying Ma, Qinchen Li, Yeqing Mao, Chaojun Wang, Liping Xie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Series:	Frontiers in Oncology
Subjects:	androgen receptor splicing variant 7 novel hormonal therapy chemotherapy prostate cancer predictor survival
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2020.572590/full

Similar Items

The characteristics of androgen receptor splice variant 7 in the treatment of hormonal sensitive prostate cancer: a systematic review and meta-analysis
by: Zhize Wang, et al.
Published: (2020-05-01)

Clinicopathological characteristics of androgen receptor splicing variant 7 (AR-V7) expression in patients with castration resistant prostate cancer: A systematic review and meta‐analysis
by: Qinchen Li, et al.
Published: (2021-09-01)

Data of relative mRNA and protein abundances of androgen receptor splice variants in castration-resistant prostate cancer
by: Tianfang Ma, et al.
Published: (2021-02-01)

Prognostic Value of Androgen Receptor Splice Variant 7 in the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-Analysis
by: Jiaxin Wang, et al.
Published: (2020-11-01)

Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy
by: Yasuomi Shimizu, et al.
Published: (2018-11-01)

LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models
by: Sergio Regufe da Mota, et al.
Published: (2018-05-01)

Androgen Receptor and Its Splicing Variant 7 Expression in Peripheral Blood Mononuclear Cells and in Circulating Tumor Cells in Metastatic Castration-Resistant Prostate Cancer
by: Mercedes Marín-Aguilera, et al.
Published: (2020-01-01)

Differential Expression of the Androgen Receptor, Splice Variants and Relaxin 2 in Renal Cancer
by: Joanna Bialek, et al.
Published: (2021-07-01)

Regulation of androgen receptor variants in prostate cancer
by: Yezi Zhu, et al.
Published: (2020-07-01)

AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel
by: Anieta M. Sieuwerts, et al.
Published: (2019-08-01)

Commentary: Meta-Analyses Reporting the Prognostic Value of Androgen Receptor Splice Variant 7 in Castration-Resistant Prostate Cancer
by: Michael W. Kattan, et al.
Published: (2020-11-01)

Mechanisms behind growth of castration-resistant prostate cancer bone metastases
by: Jernberg, Emma
Published: (2013)

Loss of an Androgen-Inactivating and Isoform-Specific HSD17B4 Splice Form Enables Emergence of Castration-Resistant Prostate Cancer
by: Hyun-Kyung Ko, et al.
Published: (2018-01-01)

Splice variants of androgen receptor and prostate cancer
by: Orazio Caffo, et al.
Published: (2016-05-01)

Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer
by: Fuqiang Ban, et al.
Published: (2021-07-01)

Alternative RNA Splicing—The Trojan Horse of Cancer Cells in Chemotherapy
by: Nikolay Mehterov, et al.
Published: (2021-07-01)

Abiraterone Rechallenge Based on Sequential Testing of Androgen Receptor Splice Variant 7 Expression in Circulating Tumor Cells: A Case Report
by: Naoya Nagaya, et al.
Published: (2020-04-01)

The Androgen Receptor in Prostate Cancer: Effect of Structure, Ligands and Spliced Variants on Therapy
by: Elisabeth A. Messner, et al.
Published: (2020-10-01)

Novel Variant of the Androgen Receptor Gene in a Patient With Complete Androgen Insensitivity Syndrome and Polyorchidism
by: Ilze Konrade, et al.
Published: (2019-01-01)

Melatonin Inhibits Androgen Receptor Splice Variant-7 (AR-V7)-Induced Nuclear Factor-Kappa B (NF-κB) Activation and NF-κB Activator-Induced AR-V7 Expression in Prostate Cancer Cells: Potential Implications for the Use of Melatonin in Castration-Resistant Prostate Cancer (CRPC) Therapy
by: Vincent Wing Sun Liu, et al.
Published: (2017-05-01)

Androgen receptor targeted therapies in metastatic castration-resistant prostate cancer – The urologists' perspective
by: Jo-Lynn Tan, et al.
Published: (2017-12-01)

Splicing Factors Have an Essential Role in Prostate Cancer Progression and Androgen Receptor Signaling
by: Ken-ichi Takayama
Published: (2019-04-01)

Deep Splicing Code: Classifying Alternative Splicing Events Using Deep Learning
by: Zakaria Louadi, et al.
Published: (2019-08-01)

Comparison of Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variant 1 in Different Stages of Endometriosis
by: Qiming Wang, et al.
Published: (2013-04-01)

Molecular Phenotyping of AR Signaling for Predicting Targeted Therapy in Castration Resistant Prostate Cancer
by: Agus Rizal A. H. Hamid, et al.
Published: (2021-08-01)

Regulation of RNA Splicing: Aberrant Splicing Regulation and Therapeutic Targets in Cancer
by: Koji Kitamura, et al.
Published: (2021-04-01)

Development of AR-V7 as a putative treatment selection marker for metastatic castration-resistant prostate cancer
by: Jun Luo
Published: (2016-01-01)

AR Splicing Variants and Resistance to AR Targeting Agents
by: Mayuko Kanayama, et al.
Published: (2021-05-01)

Registered report: androgen receptor splice variants determine taxane sensitivity in prostate cancer
by: Xiaochuan Shan, et al.
Published: (2015-09-01)

Replication study: androgen receptor splice variants determine taxane sensitivity in prostate cancer
by: Xiaochuan Shan, et al.
Published: (2018-04-01)

Blocking GRP/GRP-R signaling decreases expression of androgen receptor splice variants and inhibits tumor growth in castration-resistant prostate cancer
by: Thomas C. Case, et al.
Published: (2021-11-01)

The castration level of testosterone and hormonal resistance of prostate cancer in androgen deprivation therapy
by: I. G. Rusakov, et al.
Published: (2020-12-01)

How do we define “castration” in men on androgen deprivation therapy?
by: Sarin Itty, et al.
Published: (2020-01-01)

The Alter Retina: Alternative Splicing of Retinal Genes in Health and Disease
by: Izarbe Aísa-Marín, et al.
Published: (2021-02-01)

Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas
by: Kousuke Tanimoto, et al.
Published: (2019-12-01)

TSVdb: a web-tool for TCGA splicing variants analysis
by: Wenjie Sun, et al.
Published: (2018-05-01)

Splicing Outcomes of 5′ Splice Site GT>GC Variants That Generate Wild-Type Transcripts Differ Significantly Between Full-Length and Minigene Splicing Assays
by: Jin-Huan Lin, et al.
Published: (2021-08-01)

Placenta-specific novel splice variants of Rho GDP dissociation inhibitor β are highly expressed in cancerous cells
by: Hatakeyama Keiichi, et al.
Published: (2012-12-01)

BRCA1 Exon 11, a CERES (Composite Regulatory Element of Splicing) Element Involved in Splice Regulation
by: Claudia Tammaro, et al.
Published: (2014-07-01)

New Approach for Detection of Normal Alternative Splicing Events and Aberrant Spliceogenic Transcripts with Long-Range PCR and Deep RNA Sequencing
by: Vita Šetrajčič Dragoš, et al.
Published: (2021-07-01)

Cannot write session to /tmp/vufind_sessions/sess_cuab4dad4kjv37fvrtr79g7bl1