Antibody to mCLCA3 suppresses symptoms in a mouse model of asthma.

BACKGROUND:Asthma is a complex and heterogeneous chronic inflammatory disorder that is associated with mucous cell metaplasia and mucus hypersecretion. Functional genomic analysis indicates that mucous cell metaplasia and mucus hypersecretion depend on members of the calcium-activated chloride chann...

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Bibliographic Details
Main Authors: Liqiang Song, Dapeng Liu, Changgui Wu, Shouzhen Wu, Junlan Yang, Fangping Ren, Yan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3857274?pdf=render