Nonlinearity of mechanochemical motions in motor proteins.

The assumption of linear response of protein molecules to thermal noise or structural perturbations, such as ligand binding or detachment, is broadly used in the studies of protein dynamics. Conformational motions in proteins are traditionally analyzed in terms of normal modes and experimental data...

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Bibliographic Details
Main Authors: Yuichi Togashi, Toshio Yanagida, Alexander S Mikhailov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2887453?pdf=render