Identifying Metabolic Inhibitors to Reduce Bacterial Persistence

Bacterial persisters are rare phenotypic variants that are temporarily tolerant to high concentrations of antibiotics. We have previously discovered that stationary-phase-cell subpopulations exhibiting high redox activities were less capable of producing proteins and resuming growth upon their dilut...

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Bibliographic Details
Main Authors: Sayed Golam Mohiuddin, Thuy Hoang, Adesola Saba, Prashant Karki, Mehmet A. Orman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00472/full