ERRα as a Bridge Between Transcription and Function: Role in Liver Metabolism and Disease
As transcriptional factors, nuclear receptors (NRs) function as major regulators of gene expression. In particular, dysregulation of NR activity has been shown to significantly alter metabolic homeostasis in various contexts leading to metabolic disorders and cancers. The orphan estrogen-related rec...
Main Authors: | Hui Xia, Catherine R. Dufour, Vincent Giguère |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-04-01
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Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fendo.2019.00206/full |
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