Renal transplantation in polycythemia vera:- A rare case report from India

Polycythemia vera (PV) is a rare myeloproliferative neoplasm usually associated with JAK2 mutation. Manifestations include blood circulation disorder, hypertension and cerebral infarction. Renal disease is quite uncommon in PV and only few cases have been reported in the literature. In majority of t...

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Bibliographic Details
Main Authors: Prashant Bharat Malviya, Sanjay Maitra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Transplantation
Subjects:
Online Access:http://www.ijtonline.in/article.asp?issn=2212-0017;year=2020;volume=14;issue=4;spage=333;epage=334;aulast=
Description
Summary:Polycythemia vera (PV) is a rare myeloproliferative neoplasm usually associated with JAK2 mutation. Manifestations include blood circulation disorder, hypertension and cerebral infarction. Renal disease is quite uncommon in PV and only few cases have been reported in the literature. In majority of these cases it was considered that PVinduced glomerular hyperperfusion and hyperfiltration as a cause of CKD. PV with ESRD and undergoing successful renal transplantation is much rarer. We here report one such patient of PV who had Budd Chiari syndrome, underwent hepatic vein stenting. He developed CKD which progressed to ESRD and underwent renal transplantation. To the best of our knowledge it is first case report from India.
ISSN:2212-0017
2212-0025