Virtual docking screening and QSAR studies to explore AKT and mTOR inhibitors acting on PI3K in cancers

Virtual docking screening and QSAR studies to explore AKT and mTOR inhibitors acting on PI3K in cancers

The phosphoinositide 3-kinase (PI3K) pathway is an important regulator of cell proliferation and metabolism. PI3K activation initiates a signal transduction cascade, of which the major effectors are the kinases AKT and mTOR. Aberrant activation of the PI3K/AKT/mTOR pathway is frequently observed in...

Full description

Bibliographic Details
Main Authors: Ilham Kandoussi, Oussama Benherrif, Wiame Lakhlili, Jamal Taoufik, Azeddine Ibrahimi
Format: Article
Language:English
Published: Termedia Publishing House 2020-02-01
Series:Contemporary Oncology
Subjects:
qsar
virtual screening
pi3k/akt/mtor
docking
dual atp inhibitors
Online Access:https://www.termedia.pl/Virtual-docking-screening-and-QSAR-studies-to-explore-AKT-and-mTOR-inhibitors-acting-on-PI3K-in-cancers,3,39998,1,1.html

Internet

https://www.termedia.pl/Virtual-docking-screening-and-QSAR-studies-to-explore-AKT-and-mTOR-inhibitors-acting-on-PI3K-in-cancers,3,39998,1,1.html

Similar Items