Increased C-C chemokine receptor 2 gene expression in monocytes of severe obstructive sleep apnea patients and under intermittent hypoxia.

Increased C-C chemokine receptor 2 gene expression in monocytes of severe obstructive sleep apnea patients and under intermittent hypoxia.

Obstructive sleep apnea (OSA) is known to be a risk factor of coronary artery disease. The chemotaxis and adhesion of monocytes to the endothelium in the early atherosclerosis is important. This study aimed to investigate the effect of intermittent hypoxia, the hallmark of OSA, on the chemotaxis and...

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Bibliographic Details
Main Authors: Li-Pang Chuang, Ning-Hung Chen, Shih-Wei Lin, Ying-Ling Chang, Hsiang-Ruei Liao, Yu-Sheng Lin, I-Ju Chao, Yuling Lin, Jong-Hwei S Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4239065?pdf=render

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