Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature
We report a rare case of diffuse large B-cell lymphoma (DLBCL) of the lacrimal sac in a 50-year-old male. The incidence of primary ocular lymphoma is low and it is considered a rare disease. Moreover, reports of ocular DLBCL are uncommon and the disease remains poorly characterized. Our patient pres...
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2016-01-01
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Series: | Case Reports in Hematology |
Online Access: | http://dx.doi.org/10.1155/2016/5612749 |
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doaj-d2adfc7cc51b40c780e630fbae954fca2020-11-24T22:24:32ZengHindawi LimitedCase Reports in Hematology2090-65602090-65792016-01-01201610.1155/2016/56127495612749Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the LiteratureKevin Zarrabi0Ved Desai1Brandom Yim2Theodore G. Gabig3Department of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USADepartment of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USADepartment of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USADepartment of Medicine, Stony Brook University School of Medicine, Stony Brook, NY, USAWe report a rare case of diffuse large B-cell lymphoma (DLBCL) of the lacrimal sac in a 50-year-old male. The incidence of primary ocular lymphoma is low and it is considered a rare disease. Moreover, reports of ocular DLBCL are uncommon and the disease remains poorly characterized. Our patient presented for management of osteomyelitis and was incidentally found to have a painless swelling and cyst around his right eye. A PET/CT scan revealed hypermetabolic activity within the lacrimal sac and a subsequent excisional biopsy of the mass yielded histopathology consistent with DLBCL. Consequently, the patient underwent treatment with R-CHOP therapy. The patient responded well to chemotherapy with a substantial shrinkage in tumor burden and the disease remained localized. Herein, we present a rare case of primary ocular lymphoma, highlight the importance of early diagnosis, and review current treatment modalities.http://dx.doi.org/10.1155/2016/5612749 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kevin Zarrabi Ved Desai Brandom Yim Theodore G. Gabig |
spellingShingle |
Kevin Zarrabi Ved Desai Brandom Yim Theodore G. Gabig Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature Case Reports in Hematology |
author_facet |
Kevin Zarrabi Ved Desai Brandom Yim Theodore G. Gabig |
author_sort |
Kevin Zarrabi |
title |
Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature |
title_short |
Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature |
title_full |
Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature |
title_fullStr |
Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature |
title_full_unstemmed |
Primary Diffuse Large B-Cell Lymphoma Localized to the Lacrimal Sac: A Case Presentation and Review of the Literature |
title_sort |
primary diffuse large b-cell lymphoma localized to the lacrimal sac: a case presentation and review of the literature |
publisher |
Hindawi Limited |
series |
Case Reports in Hematology |
issn |
2090-6560 2090-6579 |
publishDate |
2016-01-01 |
description |
We report a rare case of diffuse large B-cell lymphoma (DLBCL) of the lacrimal sac in a 50-year-old male. The incidence of primary ocular lymphoma is low and it is considered a rare disease. Moreover, reports of ocular DLBCL are uncommon and the disease remains poorly characterized. Our patient presented for management of osteomyelitis and was incidentally found to have a painless swelling and cyst around his right eye. A PET/CT scan revealed hypermetabolic activity within the lacrimal sac and a subsequent excisional biopsy of the mass yielded histopathology consistent with DLBCL. Consequently, the patient underwent treatment with R-CHOP therapy. The patient responded well to chemotherapy with a substantial shrinkage in tumor burden and the disease remained localized. Herein, we present a rare case of primary ocular lymphoma, highlight the importance of early diagnosis, and review current treatment modalities. |
url |
http://dx.doi.org/10.1155/2016/5612749 |
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