A model of the innate immune response to SARS-CoV-2 in the alveolar epithelium

A model of the innate immune response to SARS-CoV-2 in the alveolar epithelium

We present a differential equation model of the innate immune response to SARS-CoV-2 within the alveolar epithelium. Critical determinants of the viral dynamics and host response, including type I and type II alveolar epithelial cells, interferons, chemokines, toxins and innate immune cells, are inc...

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Bibliographic Details
Main Authors: R. N. Leander, Y. Wu, W. Ding, D. E. Nelson, Z. Sinkala
Format: Article
Language:English
Published: The Royal Society 2021-08-01
Series:Royal Society Open Science
Subjects:
SARS-CoV-2
innate immune response
viral dynamics
within-host
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.210090

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