Protein trans-splicing of an atypical split intein showing structural flexibility and cross-reactivity.

Protein trans-splicing of an atypical split intein showing structural flexibility and cross-reactivity.

Inteins catalyze a protein splicing reaction to excise the intein from a precursor protein and join the flanking sequences (exteins) with a peptide bond. In a split intein, the intein fragments (I(N) and I(C)) can reassemble non-covalently to catalyze a trans-splicing reaction that joins the exteins...

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Bibliographic Details
Main Authors: Huiling Song, Qing Meng, Xiang-Qin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3443213?pdf=render

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