Transfer Free Energies of Test Proteins Into Crowded Protein Solutions Have Simple Dependence on Crowder Concentration

The effects of macromolecular crowding on the thermodynamic properties of test proteins are determined by the latter's transfer free energies from a dilute solution to a crowded solution. The transfer free energies in turn are determined by effective protein-crowder interactions. When these int...

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Bibliographic Details
Main Authors: Valery Nguemaha, Sanbo Qin, Huan-Xiang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00039/full