Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer

Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer

Abstract Background Though androgen deprivation therapy is the standard treatment for prostate cancer (PCa), most patients would inevitably progress to castration-resistant prostate cancer (CRPC) which is the main cause of PCa death. Therefore, the identification of novel molecular mechanism regulat...

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Bibliographic Details
Main Authors: Zhixin Ling, Xiaoyan Wang, Tao Tao, Lei Zhang, Han Guan, Zonghao You, Kai Lu, Guangyuan Zhang, Shuqiu Chen, Jianping Wu, Jinke Qian, Hui Liu, Bin Xu, Ming Chen
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Prostate cancer
MiR-193a
HOTAIR
EZH2
Progression
Online Access:http://link.springer.com/article/10.1186/s13046-017-0629-7

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http://link.springer.com/article/10.1186/s13046-017-0629-7

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