Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

Cocrystal formation rates during dry grinding and liquid-assisted grinding were investigated by X-ray powder diffractometry and Raman spectroscopy. Two polymorphic forms of piracetam were used to prepare known piracetam cocrystals as model substances, i.e.,piracetam-citric acid and piracetam-tartari...

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Bibliographic Details
Main Authors: Keith Gordon, Thomas Rades, Claudia S. Leopold, Clare J. Strachan, Marten Klukkert, Albrecht Sakmann, Korbinian A. M. Löbmann, Sönke Rehder
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Pharmaceutics
Subjects:
piracetam
cocrystal
chemometrics
formation kinetics
grinding
Online Access:http://www.mdpi.com/1999-4923/3/4/706/

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http://www.mdpi.com/1999-4923/3/4/706/

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