Optimizing Selection of the Reference Population for Genotype Imputation From Array to Sequence Variants

Optimizing Selection of the Reference Population for Genotype Imputation From Array to Sequence Variants

Imputation of high-density genotypes to whole-genome sequences (WGS) is a cost-effective method to increase the density of available markers within a population. Imputed genotypes have been successfully used for genomic selection and discovery of variants associated with traits of interest for the p...

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Bibliographic Details
Main Authors: Adrien M. Butty, Mehdi Sargolzaei, Filippo Miglior, Paul Stothard, Flavio S. Schenkel, Birgit Gredler-Grandl, Christine F. Baes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
dairy cattle
sequencing
imputation
haplotypes
accuracy
selection
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00510/full

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