What can we learn from global sensitivity analysis of biochemical systems?

Most biological models of intermediate size, and probably all large models, need to cope with the fact that many of their parameter values are unknown. In addition, it may not be possible to identify these values unambiguously on the basis of experimental data. This poses the question how reliable p...

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Bibliographic Details
Main Authors: Edward Kent, Stefan Neumann, Ursula Kummer, Pedro Mendes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828278?pdf=render