Invariant NKT Cell Lines Derived from the NOD·H2h4 Mouse Enhance Autoimmune Thyroiditis

Invariant NKT Cell Lines Derived from the NOD·H2h4 Mouse Enhance Autoimmune Thyroiditis

To study the role of invariant Natural Killer T cell (iNKT) cells in autoimmune thyroiditis, we derived two iNKT cell lines from the spleens of NOD·H2h4 mice, a strain that develops spontaneous autoimmune thyroiditis exacerbated by excess dietary iodine. The two lines were CD1d-restricted and expr...

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Bibliographic Details
Main Authors:	Rajni B. Sharma, Xiaoguang Fan, Patrizio Caturegli, Noel R. Rose, C. Lynne Burek
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	Journal of Thyroid Research
Online Access:	http://dx.doi.org/10.4061/2011/895923

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