Identification and Characterization of Alternatively Spliced Transcript Isoforms of <i>IRX4</i> in Prostate Cancer

Identification and Characterization of Alternatively Spliced Transcript Isoforms of <i>IRX4</i> in Prostate Cancer

Alternative splicing (AS) is tightly regulated to maintain genomic stability in humans. However, tumor growth, metastasis and therapy resistance benefit from aberrant RNA splicing. Iroquois-class homeodomain protein 4 (IRX4) is a TALE homeobox transcription factor which has been implicated in prosta...

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Bibliographic Details
Main Authors: Achala Fernando, Chamikara Liyanage, Afshin Moradi, Panchadsaram Janaththani, Jyotsna Batra
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Genes
Subjects:
prostate cancer
IRX4
alternative splicing
transcript
isoforms
Online Access:https://www.mdpi.com/2073-4425/12/5/615

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