Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection

<p>Abstract</p> <p>Background</p> <p>Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is one of the key components in LC-MS data pre-processing.</p> &l...

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Bibliographic Details
Main Authors: Peng Hesen, Yu Tianwei
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/559