Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications

In the last half-century, the development of biodegradable polyesters for biomedical applications has advanced significantly. Biodegradable polyester materials containing external stimuli-sensitive linkages are favored in the development of therapeutic devices for pharmacological applications such a...

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Main Authors:	Tomáš Urbánek, Eliézer Jäger, Alessandro Jäger, Martin Hrubý
Format:	Article
Language:	English
Published:	MDPI AG 2019-06-01
Series:	Polymers
Subjects:	polyester polycondensation ring-opening stimuli-sensitive drug delivery biodegradability medical application
Online Access:	https://www.mdpi.com/2073-4360/11/6/1061

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spelling	doaj-d240cdf011324ae18dbbf3f686d35bd42020-11-25T02:14:48ZengMDPI AGPolymers2073-43602019-06-01116106110.3390/polym11061061polym11061061Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical ApplicationsTomáš Urbánek0Eliézer Jäger1Alessandro Jäger2Martin Hrubý3Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech RepublicInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech RepublicInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech RepublicInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského náměstí 2, 162 00 Prague 6, Czech RepublicIn the last half-century, the development of biodegradable polyesters for biomedical applications has advanced significantly. Biodegradable polyester materials containing external stimuli-sensitive linkages are favored in the development of therapeutic devices for pharmacological applications such as delivery vehicles for controlled/sustained drug release. These selectively biodegradable polyesters degrade after particular external stimulus (e.g., pH or redox potential change or the presence of certain enzymes). This review outlines the current development of biodegradable synthetic polyesters materials able to undergo hydrolytic or enzymatic degradation for various biomedical applications, including tissue engineering, temporary implants, wound healing and drug delivery.https://www.mdpi.com/2073-4360/11/6/1061polyesterpolycondensationring-openingstimuli-sensitivedrug deliverybiodegradabilitymedical application
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Tomáš Urbánek Eliézer Jäger Alessandro Jäger Martin Hrubý
spellingShingle	Tomáš Urbánek Eliézer Jäger Alessandro Jäger Martin Hrubý Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications Polymers polyester polycondensation ring-opening stimuli-sensitive drug delivery biodegradability medical application
author_facet	Tomáš Urbánek Eliézer Jäger Alessandro Jäger Martin Hrubý
author_sort	Tomáš Urbánek
title	Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications
title_short	Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications
title_full	Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications
title_fullStr	Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications
title_full_unstemmed	Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications
title_sort	selectively biodegradable polyesters: nature-inspired construction materials for future biomedical applications
publisher	MDPI AG
series	Polymers
issn	2073-4360
publishDate	2019-06-01
description	In the last half-century, the development of biodegradable polyesters for biomedical applications has advanced significantly. Biodegradable polyester materials containing external stimuli-sensitive linkages are favored in the development of therapeutic devices for pharmacological applications such as delivery vehicles for controlled/sustained drug release. These selectively biodegradable polyesters degrade after particular external stimulus (e.g., pH or redox potential change or the presence of certain enzymes). This review outlines the current development of biodegradable synthetic polyesters materials able to undergo hydrolytic or enzymatic degradation for various biomedical applications, including tissue engineering, temporary implants, wound healing and drug delivery.
topic	polyester polycondensation ring-opening stimuli-sensitive drug delivery biodegradability medical application
url	https://www.mdpi.com/2073-4360/11/6/1061
work_keys_str_mv	AT tomasurbanek selectivelybiodegradablepolyestersnatureinspiredconstructionmaterialsforfuturebiomedicalapplications AT eliezerjager selectivelybiodegradablepolyestersnatureinspiredconstructionmaterialsforfuturebiomedicalapplications AT alessandrojager selectivelybiodegradablepolyestersnatureinspiredconstructionmaterialsforfuturebiomedicalapplications AT martinhruby selectivelybiodegradablepolyestersnatureinspiredconstructionmaterialsforfuturebiomedicalapplications
_version_	1724899662885814272

Selectively Biodegradable Polyesters: Nature-Inspired Construction Materials for Future Biomedical Applications

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