Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.

BACKGROUND:Glycerol nucleic acid (GNA) has an acyclic phosphoglycerol backbone repeat-unit, but forms stable duplexes based on Watson-Crick base-pairing. Because of its structural simplicity, GNA is of particular interest with respect to the possibility of evolving functional polymers by in vitro se...

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Bibliographic Details
Main Authors: Jesse J Chen, Ching-Hsuan Tsai, Xin Cai, Allen T Horhota, Larry W McLaughlin, Jack W Szostak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2654545?pdf=render