Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans
Stephanie Peters, Ben Pascoe, et al. use whole-genome sequencing and phenotypic analysis of clinical strains from patients to identify potential genetic factors involved in irritable bowel syndrome resulting from Campylobacter jejuni infection. Their data suggest that genes involved in the bacterial...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2021-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02554-8 |
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doaj-d22cc24a83004456be1c4f98ca2c592e2021-09-05T11:21:01ZengNature Publishing GroupCommunications Biology2399-36422021-08-014111710.1038/s42003-021-02554-8Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humansStephanie Peters0Ben Pascoe1Zuowei Wu2Sion C. Bayliss3Ximin Zeng4Adam Edwinson5Sakteesh Veerabadhran-Gurunathan6Selina Jawahir7Jessica K. Calland8Evangelos Mourkas9Robin Patel10Terra Wiens11Marijke Decuir12David Boxrud13Kirk Smith14Craig T. Parker15Gianrico Farrugia16Qijing Zhang17Samuel K. Sheppard18Madhusudan Grover19Department of Gastroenterology and Hepatology, Mayo ClinicThe Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Claverton DownDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State UniversityThe Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Claverton DownDepartment of Gastroenterology and Hepatology, Mayo ClinicDepartment of Gastroenterology and Hepatology, Mayo ClinicDepartment of Gastroenterology and Hepatology, Mayo ClinicMinnesota Department of HealthThe Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Claverton DownThe Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Claverton DownDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo ClinicDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo ClinicDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo ClinicDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo ClinicDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo ClinicUnited States Department of AgricultureDepartment of Gastroenterology and Hepatology, Mayo ClinicDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State UniversityThe Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Claverton DownDepartment of Gastroenterology and Hepatology, Mayo ClinicStephanie Peters, Ben Pascoe, et al. use whole-genome sequencing and phenotypic analysis of clinical strains from patients to identify potential genetic factors involved in irritable bowel syndrome resulting from Campylobacter jejuni infection. Their data suggest that genes involved in the bacterial stress response and biosynthetic pathways may contribute toward irritable bowel syndrome, providing further insight into links between Campylobacter genotypes and risk of disease.https://doi.org/10.1038/s42003-021-02554-8 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Stephanie Peters Ben Pascoe Zuowei Wu Sion C. Bayliss Ximin Zeng Adam Edwinson Sakteesh Veerabadhran-Gurunathan Selina Jawahir Jessica K. Calland Evangelos Mourkas Robin Patel Terra Wiens Marijke Decuir David Boxrud Kirk Smith Craig T. Parker Gianrico Farrugia Qijing Zhang Samuel K. Sheppard Madhusudan Grover |
| spellingShingle |
Stephanie Peters Ben Pascoe Zuowei Wu Sion C. Bayliss Ximin Zeng Adam Edwinson Sakteesh Veerabadhran-Gurunathan Selina Jawahir Jessica K. Calland Evangelos Mourkas Robin Patel Terra Wiens Marijke Decuir David Boxrud Kirk Smith Craig T. Parker Gianrico Farrugia Qijing Zhang Samuel K. Sheppard Madhusudan Grover Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans Communications Biology |
| author_facet |
Stephanie Peters Ben Pascoe Zuowei Wu Sion C. Bayliss Ximin Zeng Adam Edwinson Sakteesh Veerabadhran-Gurunathan Selina Jawahir Jessica K. Calland Evangelos Mourkas Robin Patel Terra Wiens Marijke Decuir David Boxrud Kirk Smith Craig T. Parker Gianrico Farrugia Qijing Zhang Samuel K. Sheppard Madhusudan Grover |
| author_sort |
Stephanie Peters |
| title |
Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans |
| title_short |
Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans |
| title_full |
Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans |
| title_fullStr |
Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans |
| title_full_unstemmed |
Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans |
| title_sort |
campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans |
| publisher |
Nature Publishing Group |
| series |
Communications Biology |
| issn |
2399-3642 |
| publishDate |
2021-08-01 |
| description |
Stephanie Peters, Ben Pascoe, et al. use whole-genome sequencing and phenotypic analysis of clinical strains from patients to identify potential genetic factors involved in irritable bowel syndrome resulting from Campylobacter jejuni infection. Their data suggest that genes involved in the bacterial stress response and biosynthetic pathways may contribute toward irritable bowel syndrome, providing further insight into links between Campylobacter genotypes and risk of disease. |
| url |
https://doi.org/10.1038/s42003-021-02554-8 |
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