Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses
SUMMARY Beside their analgesic properties, opiates exert beneficial effects on the intestinal wound healing response. In this study, we investigated the role of μ-opioid receptor (MOR) signaling on the unfolded protein response (UPR) using a novel zebrafish model of NSAID-induced intestinal injury....
Main Authors: | Jason R. Goldsmith, Jordan L. Cocchiaro, John F. Rawls, Christian Jobin |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-01-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/6/1/146 |
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