Immunological Cross-Reactivity of an Ancestral and the Most Recent Pandemic Norovirus GII.4 Variant

Immunological Cross-Reactivity of an Ancestral and the Most Recent Pandemic Norovirus GII.4 Variant

Norovirus (NoV) genotype GII.4 is responsible for the majority of NoV infections causing pandemics every few years. A NoV virus-like particle (VLP)-based vaccine should optimally cover the high antigenic variation within the GII.4 genotype. We compared the immune responses generated by VLPs of the a...

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Bibliographic Details
Main Authors: Kirsi Tamminen, Maria Malm, Timo Vesikari, Vesna Blazevic
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Viruses
Subjects:
norovirus
ancestor
variant
GII.4
immune responses
cross-reactivity
blocking antibodies
NERK motif
Online Access:https://www.mdpi.com/1999-4915/11/2/91

Internet

https://www.mdpi.com/1999-4915/11/2/91

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