Tauroursodeoxycholic Acid Protects Retinal and Visual Function in a Mouse Model of Type 1 Diabetes

Tauroursodeoxycholic Acid Protects Retinal and Visual Function in a Mouse Model of Type 1 Diabetes

Purpose: Previous studies demonstrated that systemic treatment with tauroursodeoxycholic acid (TUDCA) is protective in in vivo mouse models of retinal degeneration and in culture models of hyperglycemia. This study tested the hypothesis that TUDCA will preserve visual and retinal function in a mouse...

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Bibliographic Details
Main Authors: Jieming Fu, Moe H. Aung, Megan C. Prunty, Adam M. Hanif, Lauren M. Hutson, Jeffrey H. Boatright, Machelle T. Pardue
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
diabetic retinopathy
tauroursodeoxycholic acid
retina
mouse model
electroretinogram
optomotor response
Online Access:https://www.mdpi.com/1999-4923/13/8/1154

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