On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy

On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy

Dual-energy computed tomography enables the determination of relative electron density and effective atomic number. As this can increase accuracy in radiotherapy treatment planning, a substantial number of algorithms for the determination of the two quantities has been suggested – most of them based...

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Main Authors: Christian Möhler, Patrick Wohlfahrt, Christian Richter, Steffen Greilich
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Physics and Imaging in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405631617300611
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spelling doaj-d220791a40ad40a28648608f733663c32020-11-24T22:54:20ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162018-01-015108110On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapyChristian Möhler0Patrick Wohlfahrt1Christian Richter2Steffen Greilich3German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), 69120 Heidelberg, GermanyOncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden – Rossendorf, 01307 Dresden, Germany; Helmholtz-Zentrum Dresden – Rossendorf, Institute of Radiooncology – OncoRay, 01307 Dresden, GermanyOncoRay – National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden – Rossendorf, 01307 Dresden, Germany; Helmholtz-Zentrum Dresden – Rossendorf, Institute of Radiooncology – OncoRay, 01307 Dresden, Germany; Department of Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany; German Cancer Consortium (DKTK), 01307 Dresden, GermanyGerman Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), 69120 Heidelberg, Germany; Corresponding author at: German Cancer Research Center (DKFZ), Division of Medical Physics in Radiation Oncology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.Dual-energy computed tomography enables the determination of relative electron density and effective atomic number. As this can increase accuracy in radiotherapy treatment planning, a substantial number of algorithms for the determination of the two quantities has been suggested – most of them based on reconstructed CT images. We show that many of these methods share a common theoretical framework. Equations can be transformed from one method to the other by re-definition of the calibration parameters. We suggest that further work should be spent on practical calibration and the reliability of CT numbers rather than on the theoretical framework. Keywords: Material characterization, Radiotherapy, Treatment planning, Dose calculation, Proton and ion beam therapyhttp://www.sciencedirect.com/science/article/pii/S2405631617300611
collection DOAJ
language English
format Article
sources DOAJ
author Christian Möhler
Patrick Wohlfahrt
Christian Richter
Steffen Greilich
spellingShingle Christian Möhler
Patrick Wohlfahrt
Christian Richter
Steffen Greilich
On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy
Physics and Imaging in Radiation Oncology
author_facet Christian Möhler
Patrick Wohlfahrt
Christian Richter
Steffen Greilich
author_sort Christian Möhler
title On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy
title_short On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy
title_full On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy
title_fullStr On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy
title_full_unstemmed On the equivalence of image-based dual-energy CT methods for the determination of electron density and effective atomic number in radiotherapy
title_sort on the equivalence of image-based dual-energy ct methods for the determination of electron density and effective atomic number in radiotherapy
publisher Elsevier
series Physics and Imaging in Radiation Oncology
issn 2405-6316
publishDate 2018-01-01
description Dual-energy computed tomography enables the determination of relative electron density and effective atomic number. As this can increase accuracy in radiotherapy treatment planning, a substantial number of algorithms for the determination of the two quantities has been suggested – most of them based on reconstructed CT images. We show that many of these methods share a common theoretical framework. Equations can be transformed from one method to the other by re-definition of the calibration parameters. We suggest that further work should be spent on practical calibration and the reliability of CT numbers rather than on the theoretical framework. Keywords: Material characterization, Radiotherapy, Treatment planning, Dose calculation, Proton and ion beam therapy
url http://www.sciencedirect.com/science/article/pii/S2405631617300611
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AT patrickwohlfahrt ontheequivalenceofimagebaseddualenergyctmethodsforthedeterminationofelectrondensityandeffectiveatomicnumberinradiotherapy
AT christianrichter ontheequivalenceofimagebaseddualenergyctmethodsforthedeterminationofelectrondensityandeffectiveatomicnumberinradiotherapy
AT steffengreilich ontheequivalenceofimagebaseddualenergyctmethodsforthedeterminationofelectrondensityandeffectiveatomicnumberinradiotherapy
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