ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

Erythropoietin (EPO) is a key regulator of erythropoiesis. The embryonic liver is the main site of erythropoietin synthesis, after which the kidney takes over. The adult liver retains the ability to express EPO, and we discovered here new players of this transcription, distinct from the classical hy...

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Bibliographic Details
Main Authors: Rozenn Riou, Meriem Ladli, Sabine Gerbal-Chaloin, Pascale Bossard, Angélique Gougelet, Cécile Godard, Robin Loesch, Isabelle Lagoutte, Franck Lager, Julien Calderaro, Alexandre Dos Santos, Zhong Wang, Frédérique Verdier, Sabine Colnot
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-10-01
Series:eLife
Subjects:
chromatin remodeling
Wnt signaling
epo transcription
liver physiopathology
Online Access:https://elifesciences.org/articles/53550

Internet

https://elifesciences.org/articles/53550

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