Fibronectin glycation increases IGF-I induced proliferation of human aortic smooth muscle cells

Fibronectin glycation increases IGF-I induced proliferation of human aortic smooth muscle cells

<p>Abstract</p> <p>The advanced glycation end products, namely AGEs, contribute to long-termed complications of diabetes mellitus, including macroangiopathy, where smooth muscle cells (SMC) proliferation stimulated by platelet-derived growth factor (PDGF) isoforms and insulin-like...

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Bibliographic Details
Main Authors: Corrêa-Giannella Maria, de Azevedo Maria Regina, LeRoith Derek, Giannella-Neto Daniel
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Diabetes mellitus
Advanced glycation end products (AGE)
Smooth muscle cells
PDGF
IGF-I
IGFBP-4
Online Access:http://www.dmsjournal.com/content/4/1/19

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