First case of AML with rare chromosome translocations: a case report of twins

First case of AML with rare chromosome translocations: a case report of twins

Abstract Background Leukemia is different from solid tumor by harboring genetic rearrangements that predict prognosis and guide treatment strategy. PML-RARA, RUNX1-RUNX1T1, and KMT2A-rearrangement are common genetic rearrangements that drive the development of acute myeloid leukemia (AML). By contra...

Full description

Bibliographic Details
Main Authors: Lin Wang, Yanhua Sun, Yanli Sun, Lingbin Meng, Xin Xu
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
AML
Genetic rearrangement
FLT3/ITD
WGS
Online Access:http://link.springer.com/article/10.1186/s12885-018-4396-4

Similar Items

Similar Items